Acute toxicity of the dissociating veterinary antibiotics trimethoprim to Willow trees at varying pH.
Identifieur interne : 001736 ( Main/Exploration ); précédent : 001735; suivant : 001737Acute toxicity of the dissociating veterinary antibiotics trimethoprim to Willow trees at varying pH.
Auteurs : Ondrej Mikes [République tchèque] ; Stefan TrappSource :
- Bulletin of environmental contamination and toxicology [ 1432-0800 ] ; 2010.
Descripteurs français
- KwdFr :
- Antibactériens (toxicité), Concentration en ions d'hydrogène (MeSH), Médicaments vétérinaires (toxicité), Polluants du sol (toxicité), Salix (effets des médicaments et des substances chimiques), Tests de toxicité aigüe (MeSH), Transpiration des plantes (effets des médicaments et des substances chimiques), Triméthoprime (toxicité).
- MESH :
- effets des médicaments et des substances chimiques : Salix, Transpiration des plantes.
- toxicité : Antibactériens, Médicaments vétérinaires, Polluants du sol, Triméthoprime.
- Concentration en ions d'hydrogène, Tests de toxicité aigüe.
English descriptors
- KwdEn :
- MESH :
- chemical , toxicity : Anti-Bacterial Agents, Soil Pollutants, Trimethoprim, Veterinary Drugs.
- drug effects : Plant Transpiration, Salix.
- Hydrogen-Ion Concentration, Toxicity Tests, Acute.
Abstract
The willow tree acute toxicity test was applied to determine the acute toxicity of the neutral and the ionic form of the antibiotic trimethoprim (TMP) to trees. The pKa of the weak base TMP is at 7.2, and the toxicity testing was done at low (pH 4.3), medium (pH 6.4) and high pH (pH 8.15). The test gave toxic effects, i.e. reduced transpiration at an external concentration of 100 mg/L TMP at medium and high pH, where the neutral form of TMP dominates. At an external concentration of 1,000 mg/L, also at low pH an effect occurred, but it was less pronounced than at medium pH.
DOI: 10.1007/s00128-010-0150-6
PubMed: 21088823
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Acute toxicity of the dissociating veterinary antibiotics trimethoprim to Willow trees at varying pH.</title><author><name sortKey="Mikes, Ondrej" sort="Mikes, Ondrej" uniqKey="Mikes O" first="Ondrej" last="Mikes">Ondrej Mikes</name><affiliation wicri:level="3"><nlm:affiliation>Masaryk University, Faculty of Science, Research Centre for Toxic Compounds in the Environment, RECETOX, Kamenice 126, Brno, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Masaryk University, Faculty of Science, Research Centre for Toxic Compounds in the Environment, RECETOX, Kamenice 126, Brno</wicri:regionArea><placeName><settlement type="city">Brno</settlement><region>Moravie</region></placeName></affiliation></author><author><name sortKey="Trapp, Stefan" sort="Trapp, Stefan" uniqKey="Trapp S" first="Stefan" last="Trapp">Stefan Trapp</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:21088823</idno><idno type="pmid">21088823</idno><idno type="doi">10.1007/s00128-010-0150-6</idno><idno type="wicri:Area/Main/Corpus">001612</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001612</idno><idno type="wicri:Area/Main/Curation">001612</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001612</idno><idno type="wicri:Area/Main/Exploration">001612</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Acute toxicity of the dissociating veterinary antibiotics trimethoprim to Willow trees at varying pH.</title><author><name sortKey="Mikes, Ondrej" sort="Mikes, Ondrej" uniqKey="Mikes O" first="Ondrej" last="Mikes">Ondrej Mikes</name><affiliation wicri:level="3"><nlm:affiliation>Masaryk University, Faculty of Science, Research Centre for Toxic Compounds in the Environment, RECETOX, Kamenice 126, Brno, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Masaryk University, Faculty of Science, Research Centre for Toxic Compounds in the Environment, RECETOX, Kamenice 126, Brno</wicri:regionArea><placeName><settlement type="city">Brno</settlement><region>Moravie</region></placeName></affiliation></author><author><name sortKey="Trapp, Stefan" sort="Trapp, Stefan" uniqKey="Trapp S" first="Stefan" last="Trapp">Stefan Trapp</name></author></analytic><series><title level="j">Bulletin of environmental contamination and toxicology</title><idno type="eISSN">1432-0800</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Bacterial Agents (toxicity)</term><term>Hydrogen-Ion Concentration (MeSH)</term><term>Plant Transpiration (drug effects)</term><term>Salix (drug effects)</term><term>Soil Pollutants (toxicity)</term><term>Toxicity Tests, Acute (MeSH)</term><term>Trimethoprim (toxicity)</term><term>Veterinary Drugs (toxicity)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Antibactériens (toxicité)</term><term>Concentration en ions d'hydrogène (MeSH)</term><term>Médicaments vétérinaires (toxicité)</term><term>Polluants du sol (toxicité)</term><term>Salix (effets des médicaments et des substances chimiques)</term><term>Tests de toxicité aigüe (MeSH)</term><term>Transpiration des plantes (effets des médicaments et des substances chimiques)</term><term>Triméthoprime (toxicité)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Soil Pollutants</term><term>Trimethoprim</term><term>Veterinary Drugs</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Plant Transpiration</term><term>Salix</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Salix</term><term>Transpiration des plantes</term></keywords><keywords scheme="MESH" qualifier="toxicité" xml:lang="fr"><term>Antibactériens</term><term>Médicaments vétérinaires</term><term>Polluants du sol</term><term>Triméthoprime</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Hydrogen-Ion Concentration</term><term>Toxicity Tests, Acute</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Concentration en ions d'hydrogène</term><term>Tests de toxicité aigüe</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The willow tree acute toxicity test was applied to determine the acute toxicity of the neutral and the ionic form of the antibiotic trimethoprim (TMP) to trees. The pKa of the weak base TMP is at 7.2, and the toxicity testing was done at low (pH 4.3), medium (pH 6.4) and high pH (pH 8.15). The test gave toxic effects, i.e. reduced transpiration at an external concentration of 100 mg/L TMP at medium and high pH, where the neutral form of TMP dominates. At an external concentration of 1,000 mg/L, also at low pH an effect occurred, but it was less pronounced than at medium pH.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21088823</PMID><DateCompleted><Year>2011</Year><Month>01</Month><Day>18</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1432-0800</ISSN><JournalIssue CitedMedium="Internet"><Volume>85</Volume><Issue>6</Issue><PubDate><Year>2010</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Bulletin of environmental contamination and toxicology</Title><ISOAbbreviation>Bull Environ Contam Toxicol</ISOAbbreviation></Journal><ArticleTitle>Acute toxicity of the dissociating veterinary antibiotics trimethoprim to Willow trees at varying pH.</ArticleTitle><Pagination><MedlinePgn>556-61</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00128-010-0150-6</ELocationID><Abstract><AbstractText>The willow tree acute toxicity test was applied to determine the acute toxicity of the neutral and the ionic form of the antibiotic trimethoprim (TMP) to trees. The pKa of the weak base TMP is at 7.2, and the toxicity testing was done at low (pH 4.3), medium (pH 6.4) and high pH (pH 8.15). The test gave toxic effects, i.e. reduced transpiration at an external concentration of 100 mg/L TMP at medium and high pH, where the neutral form of TMP dominates. At an external concentration of 1,000 mg/L, also at low pH an effect occurred, but it was less pronounced than at medium pH.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mikes</LastName><ForeName>Ondrej</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Masaryk University, Faculty of Science, Research Centre for Toxic Compounds in the Environment, RECETOX, Kamenice 126, Brno, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trapp</LastName><ForeName>Stefan</ForeName><Initials>S</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2010</Year><Month>11</Month><Day>19</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Bull Environ Contam Toxicol</MedlineTA><NlmUniqueID>0046021</NlmUniqueID><ISSNLinking>0007-4861</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012989">Soil Pollutants</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019155">Veterinary Drugs</NameOfSubstance></Chemical><Chemical><RegistryNumber>AN164J8Y0X</RegistryNumber><NameOfSubstance UI="D014295">Trimethoprim</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006863" MajorTopicYN="N">Hydrogen-Ion Concentration</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018526" MajorTopicYN="N">Plant Transpiration</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032108" MajorTopicYN="N">Salix</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012989" MajorTopicYN="N">Soil Pollutants</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="N">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D023382" MajorTopicYN="N">Toxicity Tests, Acute</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014295" MajorTopicYN="N">Trimethoprim</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019155" MajorTopicYN="N">Veterinary Drugs</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2010</Year><Month>05</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2010</Year><Month>10</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>11</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>11</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2011</Year><Month>1</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">21088823</ArticleId><ArticleId IdType="doi">10.1007/s00128-010-0150-6</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République tchèque</li></country><region><li>Moravie</li></region><settlement><li>Brno</li></settlement></list><tree><noCountry><name sortKey="Trapp, Stefan" sort="Trapp, Stefan" uniqKey="Trapp S" first="Stefan" last="Trapp">Stefan Trapp</name></noCountry><country name="République tchèque"><region name="Moravie"><name sortKey="Mikes, Ondrej" sort="Mikes, Ondrej" uniqKey="Mikes O" first="Ondrej" last="Mikes">Ondrej Mikes</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/WillowV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001736 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001736 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= WillowV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:21088823
|texte= Acute toxicity of the dissociating veterinary antibiotics trimethoprim to Willow trees at varying pH.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21088823" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a WillowV1
| This area was generated with Dilib version V0.6.37. |  |